The VITESSE algorithm for rapid exact multilocus linkage analysis via genotype set-recoding and fuzzy inheritance.

doi:10.1038/ng1295-402

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Article

The VITESSE algorithm for rapid exact multilocus linkage analysis via genotype set-recoding and fuzzy inheritance.

Nature genetics - 1 Dec 1995

O'Connell J R, Weeks D E

Abstract excerpt

As genetic marker maps have improved, multipoint linkage analysis has become a crucial part of all disease mapping studies. Paradoxically, multipoint lod scores become increasingly difficult to compute, particularly as the numbers of markers, marker alleles and untyped people increase. We have so...

Topics

Algorithms
Chromosome Mapping
Female
Genetic Linkage
Genetic Markers
Genotype
Humans
Likelihood Functions
Male
Pedigree
Software

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