Article
The VITESSE algorithm for rapid exact multilocus linkage analysis via genotype set-recoding and fuzzy inheritance.
Nature genetics - 1 Dec 1995
O'Connell J R, Weeks D E
Abstract excerpt
As genetic marker maps have improved, multipoint linkage analysis has become a crucial part of all disease mapping studies. Paradoxically, multipoint lod scores become increasingly difficult to compute, particularly as the numbers of markers, marker alleles and untyped people increase. We have solved this problem by using a novel set-recording scheme to recode each person's genotype and 'fuzzy inheritance' to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.