Article
Flow cytometric identification of a minority population of MHC class II positive cells in the normal rat retina distinct from CD45lowCD11b/c+CD4low parenchymal microglia.
The British journal of ophthalmology - 1 Sept 1995
Dick A D, Ford A L, Forrester J V, Sedgwick J D
Abstract excerpt
AIMS: This study aimed to isolate and classify by flow cytometry, the cell surface phenotype of microglia in the normal rat retina with a view to identifying putative antigen presenting cells (APC) within the retina, which has to date not been possible by immunohistochemistry. METHODS: Normal rat retinal microglia were isolated and classified using a modification of an isolation technique employing graduated...
Topics
- Animals
- CD4 Antigens
- Central Nervous System
- Flow Cytometry
- Integrin alphaXbeta2
- Leukocyte Common Antigens
- Macrophage-1 Antigen
- Major Histocompatibility Complex
- Microglia
- Phenotype