Article
An Ael allele-specific nucleotide insertion at the blood group ABO locus and its detection using a sequence-specific polymerase chain reaction.
Biochemical and biophysical research communications - 13 Nov 1995
Olsson M L, Thuresson B, Chester M A
Abstract excerpt
Genomic DNA from each of four Acl individuals (genotypes AO1, AO1var, AO2) and one AclB individual was used as a template for amplifying exons 6 and 7 of the ABO genes, which were subsequently sequenced. In all the Ael alleles a single nucleotide insertion, compared to the A consensus sequence, w...
Topics
- ABO Blood-Group System
- Alleles
- Base Sequence
- Consensus Sequence
- DNA
- DNA Primers
- DNA Transposable Elements
- Exons
- Female
- Genotype
- Humans
- Male
- Molecular Sequence Data
- Oligonucleotides, Antisense
- Pedigree
- Polymerase Chain Reaction
- Templates, Genetic