Extracellular matrix stoichiometry in osteoblasts from patients with osteogenesis imperfecta.

doi:10.1002/jbmr.5650100718

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Article

Extracellular matrix stoichiometry in osteoblasts from patients with osteogenesis imperfecta.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jul 1995

Fedarko N S, Robey P G, Vetter U K

Abstract excerpt

In previous work, we compared the steady-state levels of specific matrix components in human bone cells derived from patients with osteogenesis imperfecta (OI) to those of age-matched controls. A remarkable finding was the observation that there was a reduction not only in the total levels of collagen, but also in osteonectin and three proteoglycans (a large chondroitin sulfate proteoglycan, biglycan, and...

Topics

Adolescent
Biglycan
Cell Adhesion Molecules
Cells, Cultured
Child
Child, Preschool
Chondroitin Sulfates
Collagen
Decorin
Electrophoresis, Polyacrylamide Gel
Extracellular Matrix

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Extracellular Matrix Proteins

Female

Fibronectins

Fluorometry

Heparan Sulfate Proteoglycans

Heparitin Sulfate

Humans

Source

Open in PubMed

Identifiers

PMID: 7484289
DOI: 10.1002/jbmr.5650100718

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7484289-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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