Article
Uncoupling Cell Fate Determination from Patterned Cell Division in the <i>Drosophila</i> Eye
10 Nov 1995
Abstract excerpt
Cell proliferation and cell fate specification are under strict spatiotemporal control in the developing Drosophila eye. Cells excluded from five-cell preclusters synchronously enter a single additional cell cycle, the second mitotic wave, after which the remaining cells are sequentially recruited. When the second mitotic wave was blocked with the human cyclin-dependent kinase inhibitor p21CIP1/WAF1, each cell...
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