Article
Initiation and promotion in cancer formation: the importance of studies on intercellular communication.
The Yale journal of biology and medicine - 1 Jan 2000
Potter V R
Abstract excerpt
Three major theories of cancer--somatic mutation, virus causation, and faulty differentiation--are proposed to involve alterations in DNA structure. Each results finally in terms of failures in the normal intercellular communication that involves feedback between differentiated cells acting on le...
Topics
- Animals
- Carcinogens
- Cell Communication
- Cell Differentiation
- Cell Transformation, Neoplastic
- Croton Oil
- DNA
- Disease Models, Animal
- Feedback
- Humans
- Hybrid Cells
- Liver Neoplasms
- Liver Neoplasms, Experimental
- Mice
- Mutation
- Rabbits
- Rats
- Skin Neoplasms