Fidelity in transcription assessed by DNA-dependent RNA polymerases.

doi:10.1016/s0300-9084(82)80095-3

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Article

Fidelity in transcription assessed by DNA-dependent RNA polymerases.

Biochimie - 1 Jan 2000

Singer B

Abstract excerpt

The use of in vitro transcription of polynucleotides by prokaryotic and eukaryotic DNA-dependent RNA polymerases has proven of great usefulness in detecting mutagenic base modifications. Quite similar results are obtained with ribo- and deoxyribopolymers as templates, and with Mg2+ and Mn2+ at op...

Topics

Animals
Cattle
DNA-Directed RNA Polymerases
Escherichia coli
Magnesium
Manganese
Mutagens
Mutation
Templates, Genetic
Thymus Gland
Transcription, Genetic

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