Article
Estimation of relative electrophoretic mutation rates from rare alleles in a sample.
Annals of human biology - 1 Jan 2000
Chakraborty R, Majumder P P
Abstract excerpt
The theoretical justifications for using the number of rare alleles observed in a sample and the heterozygosity contributed by such alleles to estimate the relative electrophoretic mutation rate (REMR) are given in this note. It is shown that the estimator using the number of alleles has comparatively less bias. While the total heterozygosity contributed by all alleles at a locus has been previously used to...
Topics
- Alleles
- Heterozygote
- Homozygote
- Humans
- Mutation