Article
Interactive effect of genes associated with immunoglobulin allotypes and HLA specificities on susceptibility to Haemophilus influenzae disease.
Journal of immunogenetics - 1 Jan 2000
Granoff D M, Boies E, Squires J, Pandey J P, Suarez B, Oldfather J, Rodey G E
Abstract excerpt
Genes associated with immunoglobulin (Ig) allotype determinants are important in regulation of immune responses to bacterial polysaccharides. Furthermore, loci associated with Ig allotypes have been reported to interact with those associated with the major histocompatibility complex and affect susceptibility to certain diseases. In the present study we determined the frequencies of certain Gm phenotypes in...
Topics
- Child
- Epiglottitis
- HLA Antigens
- Haemophilus Infections
- Humans
- Immunoglobulin Allotypes
- Meningitis, Haemophilus
- Phenotype