Article
Genetic differences in the effect of ethanol on plasma corticosterone and nonesterified fatty acid in rats.
Alcoholism, clinical and experimental research - 1 Jan 2000
Pohorecky L A
Abstract excerpt
The influence of genotype on the responsiveness to ethanol in rodents was examined using biochemical measures. Nine different strains of rats were treated with saline or various doses of ethanol, and the changes in plasma corticosterone and of nonesterified free fatty acids were measured 1 hr later. It was found that the BUF/N strain of rats had the lowest response on both measures and also had the lowest blood...
Topics
- Alcoholism
- Animals
- Corticosterone
- Disease Models, Animal
- Ethanol
- Fatty Acids, Nonesterified
- Genotype
- Humans
- Male
- Rats
- Rats, Inbred Strains