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Article

Insulin gene structure and function: a review of studies using recombinant DNA methodology.

Diabetes care - 1 Jan 2000

Permutt M A, Chirgwin J, Rotwein P, Giddings S

Abstract excerpt

This review focuses on recent advances in molecular biology as they pertain to the insulin gene and diabetes mellitus. The structure of the human insulin gene is examined, and factors related to its normal functioning in the beta cells of the pancreas are explored. DNA polymorphisms near the insulin locus and their relationship with certain types of diabetes are considered, as are recently characterized human...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 6381010
DOI: 10.2337/diacare.7.4.386

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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