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Article

Influence of Cannabinoids on Somatic Cells in vivo

30 May 2008

Abstract excerpt

Chromosomal and nuclear aberrations in bone marrow cells were studied in hybrid mice of genotype (C57BL x C3H)F1 following treatment with specific cannabinoids. In the subacute series, mice were treated for 5 consecutive days with delta 9-tetrahydrocannabinol (THC), cannabinol or cannabidiol at a dose of 10 mg/kg, the percentage of micronuclei in cannabinoid-treated mice was 3- to 5-fold greater than in the...

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PMID: 6252564
DOI: 10.1159/000137442

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