Article
Functional genetic damages and their possible role in the aging of eukaryote cells.
Biology bulletin of the Academy of Sciences of the USSR. Akademiia nauk SSSR - 1 Jan 2000
Akif'ev A P, Klimenko V V, Mutovin G R
Abstract excerpt
As a result of investigations of the functional acitivty of eukaryote cells damaged by ionizing radiation and alkylating mutagens under conditions of extreme loading, the authors have suggested that natural aging and aging accelerated by mutagens are based on a process of accumulation of function...
Topics
- Aging
- Animals
- Aziridines
- Cytochrome P-450 Enzyme System
- Kinetics
- Liver
- Liver Regeneration
- Mitosis
- Mutagens
- Mutation
- Phenobarbital
- Piperazines
- Protein Biosynthesis
- Rats
- Transcription, Genetic