Quaternionic response geometry for proteins: toward a noncommutative theory of ordered deformations.

Abstract excerpt

Protein function may depend not only on endpoint conformations but also on the ordered deformation histories through which they are reached. This distinction is relevant to allostery, conformational switching, mutation-induced rearrangements, and epistatic effects, where different perturbation sequences may produce similar visible structures while retaining distinct internal transport histories. Current...

Topics

• Proteins
• Protein Conformation
• Mutation
• Molecular Dynamics Simulation
• Algorithms
• Allosteric Regulation