Homozygous familial hypercholesterolemia (HoFH) in Canada.

doi:10.1016/j.atherosclerosis.2026.120792

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Homozygous familial hypercholesterolemia (HoFH) in Canada.

Atherosclerosis - 1 Jul 2026

Al-Baldawi Zobaida, Erzingatzian Armen, Ruel Isabelle, Brown Leslie, Sherman Mark H, Laflamme Nathalie, Bergeron Jean, Couture Patrick, Paquette Martine, Baass Alexis, Brisson Diane, Larouche Miriam, Gaudet Daniel, Cermakova Lubomira, Wan Darryl, Moulson Nathaniel, Francis Gordon A, Mancini G B John, Kennedy Brooke A, Hegele Robert A, Lewis Gary F, McCrindle Brian W, Cifra Barbara, Ransom Thomas, McPherson Ruth, Genest Jacques, Brunham Liam R, Iatan Iulia

Abstract excerpt

BACKGROUND AND AIMS: Homozygous familial hypercholesterolemia (HoFH) is a rare disorder of lipid metabolism, characterized by extremely elevated low-density lipoprotein cholesterol (LDL-C) levels and marked premature cardiovascular disease. The Canadian HoFH Registry was established to understand treatment patterns and clinical outcomes for this population in Canada. This study aimed to investigate the clinical...

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PMID: 42229223
DOI: 10.1016/j.atherosclerosis.2026.120792

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PCSK9

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