Genomic and ecological systems-thinking framework for pathogenic Leptospira in Puerto Rico.

Abstract excerpt

Introduction: Leptospirosis is a complex zoonotic disease requiring high-resolution surveillance. A systems-thinking framework was used to connect genomic and ecological data and map the geographic and host-based structuring of co-circulating pathogenic Leptospira lineages in Puerto Rico. Methods: Forty-four core genomes of L. interrogans, L. borgpetersenii, and L. kirschneri from human, domestic, and wildlife...

Topics

• Puerto Rico
• Animals
• Leptospira
• Humans
• Leptospirosis
• Polymorphism, Single Nucleotide
• Genomics