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Article

Genotype-Specific Clinical Response to a Lactose-Free Diet in Adult Patients Evaluated for Lactose Intolerance: Implications for Clinical Assessment.

Nutrients - 24 Aug 2026

Mirică Roxana Elena, Stefan Claudia Simona, Nechifor Alexandru, Breazu Alina, Batis Laura Maria, Soare Ioana

Abstract excerpt

Background: Lactose intolerance is a common gastrointestinal condition with variable clinical expression, often requiring both clinical and genetic evaluation. While genetic testing identifies genetic predisposition to lactase persistence or non-persistence, the relationship between specific LCT genotypes and clinical response to dietary intervention remains incompletely understood. Aim: To assess the association...

Read the complete abstract on PubMed

Topics

Humans
Lactose Intolerance
Female
Male
Adult
Retrospective Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genotype

Middle Aged

Lactase

Lactose

Genetic Predisposition to Disease

Logistic Models

Treatment Outcome

Aged

Source

Open in PubMed Open full text

Identifiers

PMID: 42738939
DOI: 10.3390/nu18172764
PMCID: PMC13566943

Genes

LCT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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Genotype-Specific Clinical Response to a Lactose-Free Diet in Adult Patients Evaluated for Lactose Intolerance: Implications for Clinical Assessment.PMID 42738939Read ↗

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