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Article

Sexual selection purges mutation load, but not overall genetic diversity, decreasing vulnerability to extinction.

Proceedings of the National Academy of Sciences of the United States of America - 15 Sept 2026

Pointer Michael D, Nash Will J, Gage Matthew J G, Chapman Tracey, Maklakov Alexei A, Richardson David S

Abstract excerpt

Theory suggests sexual selection will enhance population viability by purging deleterious alleles. However, direct genomic evidence for this fundamental idea is scarce and contradictory. We combined long-term experimental evolution with whole-genome resequencing to directly test how sexual selection affects mutation load, genomic divergence, and extinction risk in small populations (maximum Ne = 40) of Tribolium...

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Topics

Animals
Genetic Variation
Tribolium
Mutation
Sexual Selection
Extinction, Biological

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Male

Female

Selection, Genetic

Alleles

Source

Open in PubMed Open full text

Identifiers

PMID: 42709809
DOI: 10.1073/pnas.2608675123
PMCID: PMC13578823

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

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