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Article

Integrative Multi-Omics Analysis Identifies Thrombosis-Associated Molecular Features Linked to Germline Susceptibility and Immune Cell Communication in Gastric Cancer.

Chemical biology & drug design - 1 Sept 2026

Lu Xiaogang, Sun Lin, Jin Fujun, Cheng Biao, Huang Ying, Tang Yuzhu, Nie Xiaolong, Gao Feng

Abstract excerpt

Emerging evidence indicates that coagulation-related molecular programs are associated with thrombosis, tumor progression, and molecular dysregulation in gastric cancer (GC). However, thrombosis-associated molecular features in GC and their potential links to inherited susceptibility remain insufficiently understood. Integrated analyses of transcriptomic data from The Cancer Genome Atlas (TCGA) and Gene...

Read the complete abstract on PubMed

Topics

Humans
Stomach Neoplasms
Genome-Wide Association Study
Thrombosis
Multiomics
Quantitative Trait Loci

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Cell Communication

Cell Line, Tumor

Source

Open in PubMed Open full text

Identifiers

PMID: 42681916
DOI: 10.1111/cbdd.70386
PMCID: PMC13534880

Genes

GC
CRYAB
ACTN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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