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Article

Comparative Analysis of Graph Attention and Graph Convolutional Networks for Predicting Candidate SNP-miRNA-DrugInteractions in Integrated Regulatory Datasets.

Acta odontologica latinoamericana : AOL - 30 Jun 2026

Batra Varun, Yadalam Pradeep K, Ardila Carlos M

Abstract excerpt

Complex genetic and epigenetic factors, such as single-nucleotide polymorphisms (SNPs) that influence the function of microRNAs (miRNAs), are involved in periodontal inflammation and tissue regeneration. However, computational approaches for predicting potential SNP-miRNA interactions that may influence inflammatory signaling and drug responses remain limited in precision periodontology. AIM: To implement and...

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Topics

Polymorphism, Single Nucleotide
Graph Neural Networks
MicroRNAs
Humans
Machine Learning

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Identifiers

PMID: 42678111
DOI: 10.54589/aol.39/1/43
PMCID: PMC13543398

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