Emergence of a Novel, Phenotypically Difficult-to-Detect Vancomycin-Resistant Enterococcus faecium Clone (ST117/CT7799).

doi:10.1002/mbo3.70393

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Emergence of a Novel, Phenotypically Difficult-to-Detect Vancomycin-Resistant Enterococcus faecium Clone (ST117/CT7799).

MicrobiologyOpen - 1 Oct 2026

Forstner Patrick, Uitz Christine, Dabernig-Heinz Johanna, Wagner Gabriel E, Bender Jennifer, Fischer Martin, Siebenhofer David, Werner Guido, Busche Tobias, Klages Levin Joe, Rückert-Reed Christian, Steinmetz Ivo, Dichtl Karl

Abstract excerpt

A significant increase of vancomycin-resistant Enterococcus faecium (VREfm) infections was observed in South-Eastern Austria since 2024. The prolonged outbreak is caused by a novel vanB-VREfm clone (ST117/CT7799, "VREfmstyr"). This study characterizes the atypical difficult-to-detect resistance phenotype and assesses the genomic relatedness of the isolates. Patient and outbreak characteristics were investigated...

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Topics

Enterococcus faecium
Humans
Vancomycin-Resistant Enterococci
Gram-Positive Bacterial Infections
Multilocus Sequence Typing

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Microbial Sensitivity Tests

Phenotype

Anti-Bacterial Agents

Austria

Disease Outbreaks

Whole Genome Sequencing

Bacterial Proteins

Vancomycin Resistance

Vancomycin

Source

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Identifiers

PMID: 42671072
DOI: 10.1002/mbo3.70393
PMCID: PMC13528232

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