Novel, rapid, and reliable typing of vancomycin-resistant Enterococcus faecium CC17/ST80 strains using MALDI-TOF MS.

doi:10.1128/spectrum.02702-25

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Novel, rapid, and reliable typing of vancomycin-resistant Enterococcus faecium CC17/ST80 strains using MALDI-TOF MS.

Microbiology spectrum - 4 Nov 2025

Huber Silke, Brühwasser Christina, Eisele David, Lass-Flörl Cornelia, Fuchs Stefan, Govrins Miriam

Abstract excerpt

Vancomycin-resistant Enterococcus faecium (VREfm) is an important nosocomial pathogen. The recent emergence of the highly virulent clonal complex 17 (CC17) is posing a challenge for both therapeutic interventions and hospital infection control measures. Hence, prompt discrimination of CC17 VREfm from unrelated and less-virulent VREfm strains is essential for preventing its spread in hospitals and beyond. Between...

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Topics

Enterococcus faecium
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Vancomycin-Resistant Enterococci
Humans
Gram-Positive Bacterial Infections

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Whole Genome Sequencing

Bacterial Typing Techniques

Electrophoresis, Gel, Pulsed-Field

Cross Infection

Genotype

Disease Outbreaks

Bacterial Proteins

Source

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Identifiers

PMID: 41031816
DOI: 10.1128/spectrum.02702-25
PMCID: PMC12584701

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