Metabolic dysfunction-associated steatotic liver disease as a systemic disorder: extrahepatic manifestations and the need for data-driven phenotyping.

Abstract excerpt

Metabolic dysfunction-associated steatotic liver disease (MASLD) is increasingly recognized as a systemic disorder that extends beyond hepatic steatosis to involve multiple extrahepatic organs, including the cardiovascular system, kidneys, brain, pancreas, and other organ systems. This multisystem involvement is accompanied by marked heterogeneity in clinical presentation and disease progression, supporting the...

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