Major Histocompatibility Complex Genomic Regions as Candidates for Reproductive Success in Cattle: From GWAS to Post-GWAS Analysis.

doi:10.3390/genes17080895

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Article

Major Histocompatibility Complex Genomic Regions as Candidates for Reproductive Success in Cattle: From GWAS to Post-GWAS Analysis.

Genes - 30 Jul 2026

Faverzani Louíse B, Zwirtes Andreia K, Rodrigues Dinah P A, Machado Thais F, Oliveira Daniele A, Silveira Luiza C, Seixas Nathalia P, Silva Evandro N, Silva Danielly B S, Vaz Ricardo Z, Melo Thaise P

Abstract excerpt

BACKGROUND: The major histocompatibility complex (MHC) is a well-known gene complex that plays a fundamental role in immune recognition; however, its influence on reproductive processes in cattle is not yet fully established, particularly regarding how it modulates the female response to the embryo. Therefore, this study aimed to investigate the relationship between MHC genes and reproductive processes in cattle...

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