Article
Genome-wide association and expression quantitative trait loci in cattle reveals common genes regulating mammalian fertility.
Communications biology - 12 Jun 2024
Forutan Mehrnush, Engle Bailey N, Chamberlain Amanda J, Ross Elizabeth M, Nguyen Loan T, D'Occhio Michael J, Snr Alf Collins, Kho Elise A, Fordyce Geoffry, Speight Shannon, Goddard Michael E, Hayes Ben J
Abstract excerpt
Most genetic variants associated with fertility in mammals fall in non-coding regions of the genome and it is unclear how these variants affect fertility. Here we use genome-wide association summary statistics for Heifer puberty (pubertal or not at 600 days) from 27,707 Bos indicus, Bos taurus and crossbred cattle; multi-trait GWAS signals from 2119 indicine cattle for four fertility traits, including days to...
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