Article
A pangenome framework uncovers the role of deletions in repeated evolution of cave-derived traits.
Genome research - 1 Sept 2026
Roback Emma Y, X Maggs, Ricemeyer Edward S, Warlen Adam, Carroll Rachel A, Elsik Christine G, Keene Alex C, Rohner Nicolas, McGaugh Suzanne E, Warren Wesley C
Abstract excerpt
Structural variants (SVs) are increasingly recognized as key contributors to adaptive evolution, yet they remain underexplored compared with single-nucleotide variation. To understand how large-scale genomic changes shape repeated evolution, we leveraged multiple levels of sequence data across the powerful evolutionary model system of the Mexican tetra fish (Astyanax mexicanus). We constructed one of the first...
Read the complete abstract on PubMedTopics
- Animals
- Caves
- Evolution, Molecular
- Quantitative Trait Loci
- Selection, Genetic
- Genome