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Article

Loss of Conserved Noncoding Elements Likely Shaped the Evolution of Regressed Phenotypes in Cavefish.

Genome biology and evolution - 28 Nov 2025

Lal Mohan, Bhattacharya Jui, Sandhu Kuljeet Singh

Abstract excerpt

The Mexican cavefish, Astyanax mexicanus, is a captivating model for probing cave adaptations, showcasing pronounced divergence in traits like vision, brain morphology, behavior, pigmentation, metabolism, and hypoxia tolerance compared to its surface-dwelling counterpart. However, only a small number of protein-coding variants have been found in cave-morphs, leaving the vast phenotypic gap between the two morphs...

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Biological Evolution
Caves
Conserved Sequence
Evolution, Molecular
Phenotype

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PMID: 41219170
DOI: 10.1093/gbe/evaf211
PMCID: PMC12662050

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