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Article

Basic Clinical Bidirectional Empowerment: Synergistic Breakthrough in Molecular Mechanisms and Clinical Management of Small Cell Cervical Carcinoma.

International journal of molecular sciences - 29 Jul 2026

Huang Mengjia, Li Shuang

Abstract excerpt

Small cell carcinoma of the cervix (SCCC) is a rare yet highly aggressive subtype of cervical cancer (CC), characterized by early invasion, high metastatic potential, frequent recurrence, and extremely poor prognosis, which severely impairs women's physical and mental health. Currently, high-risk human papillomavirus (hr-HPV, particularly HPV18) infection is recognized as one of the core drivers underlying the...

Topics

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Carcinoma, Small Cell
RB1 gene
TP53 gene
Human Papillomavirus Viruses
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Papillomavirus Infections

Signal Transduction

Uterine Cervical Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 42589439
DOI: 10.3390/ijms27156783
PMCID: PMC13466829

Genes

RB1
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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