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Article

Multigene panel analysis of connective tissue and vascular genes in patients with a bleeding disorder of unknown cause or a cerebrovascular event.

Research and practice in thrombosis and haemostasis - 1 Jul 2026

Florquin Mona, Van Laer Christine, Kint Cyrielle, Van Geet Chris, Van Thillo Quentin, Freson Kathleen, Labarque Veerle

Abstract excerpt

Background: Bleeding disorder of unknown cause (BDUC) refers to patients with a significant bleeding phenotype despite normal hemostatic evaluation. Cerebrovascular events (CVEs) are neurologic deficits from intracerebral hemorrhages to hemorrhagic or ischemic strokes. A multigene panel for inherited connective tissue and vascular disorders (BLEED_panel) may improve diagnostic assessment. Objectives: This study...

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Identifiers

PMID: 42568836
DOI: 10.1016/j.rpth.2026.106839
PMCID: PMC13448018

Genes

COL4A1
COL4A2
ENG
COL5A1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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