Article
Impact of mutations in PRLR for hair weight, circulating prolactin concentrations, feed intake, and growth of beef cattle in a hot and humid climate.
Frontiers in endocrinology - 1 Jan 2026
Cuellar Camila J, Heredia Daniella, Infante Cangrejo Jose L, Hoorn Quinn A, Sproull Abigail J, Venturini Mauro, Tarnonsky Federico, Hincapié Samuel, DiLorenzo Nicolas, Gonella-Diaza Angela M, Oberhaus Erin L, Hansen Peter J
Abstract excerpt
Background: In cattle, mutations in the prolactin receptor gene (PRLR) causing loss of tyrosine residues important for JAK-STAT signaling result in a short hair coat and increased ability to regulate body temperature during heat stress. Such mutations, referred to as slick mutations, occur naturally and have been introduced into cattle by gene editing. Aim: Consequences of inheritance of various mutations in PRLR...
Topics
Join the communities discussing this publication.