Article
Inheritance of the SLICK1 allele of PRLR in cattle.
Animal genetics - 1 Dec 2021
Sosa F, Carmickle A T, Jiménez-Cabán E, Ortega M S, Dikmen S, Negrón-Pérez V, Jannaman E A, Baktula A, Rincon G, Larson C C, Pagán-Morales M, Denicol A C, Sonstegard T S, Hansen P J
Abstract excerpt
The slick-hair phenotype in cattle is due to one of a series of mutations in the prolactin receptor (PRLR) that cause truncation of the C-terminal region of the protein involved in JAK2/STAT5 activation during prolactin signaling. Here we evaluated whether the inheritance of the SLICK1 allele, the first slick mutation discovered, is inherited in a fashion consistent with Hardy-Weinberg equilibrium. It was...
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