Systemic Comorbidities of Keloid and Hypertrophic Scars: A Phenome-Wide Association Study in a Multiethnic U.S. Pediatric Cohort.

doi:10.1007/s40257-026-01063-w

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Article

Systemic Comorbidities of Keloid and Hypertrophic Scars: A Phenome-Wide Association Study in a Multiethnic U.S. Pediatric Cohort.

American journal of clinical dermatology - 1 Sept 2026

Vahidnezhad Fatemeh, Samieefar Noosha, Akbarzadeh Mahdi, Safari Parisa, Mentch Frank, March Michael, Tsoi Lam C, Margolis David J, Gudjonsson Johann E, Hakonarson Hakon, Vahidnezhad Hassan

Abstract excerpt

BACKGROUND: Excessive scarring (ES), including keloids and hypertrophic scars, impairs function, appearance, and quality of life in children. Its pediatric comorbidity spectrum is not well defined, limiting anticipatory guidance and multidisciplinary care. This research aims to investigate comorbidities of ES in a diverse pediatric cohort using a phenome-wide association study (PheWAS). METHODS: This...

Read the complete abstract on PubMed

Topics

Humans
Keloid
Child
Female
Cicatrix, Hypertrophic
Male

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Comorbidity

Phenotype

Child, Preschool

Adolescent

United States

Infant

Longitudinal Studies

Genome-Wide Association Study

Electronic Health Records

Source

Open in PubMed

Identifiers

PMID: 42543465
DOI: 10.1007/s40257-026-01063-w

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