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Article

Neuroprotective Potential of Spermidine in Drosophila sws Neurodegenerative Model.

Archives of insect biochemistry and physiology - 1 Aug 2026

Raspopina Anastasiia, Tkachuk Marta, Matiytsiv Nataliya

Abstract excerpt

Neurodegenerative disorders are characterized by progressive neuronal loss and functional decline, yet effective interventions remain limited. The polyamine spermidine was suggested to exert neuroprotective effects, but its concentration-dependent impact on longevity, neuronal integrity, and behavior remains still not well studied. Here, we investigated the effects of spermidine on lifespan, behavioral responses,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42541426
DOI: 10.1002/arch.70201
PMCID: PMC13428469

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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