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Article

Thrombophilia-related gene variants may be linked to polycystic ovary syndrome susceptibility and its related traits.

Biomarkers in medicine - 1 Jul 2026

Dadachanji Roshan, Khavale Sushma, Joshi Nanda, Patil Anushree, Mukherjee Srabani

Abstract excerpt

BACKGROUND: Polycystic ovary syndrome (PCOS) is a prevalent endocrinopathy in reproductive-aged women having both gynecological and metabolic comorbidities. PCOS increases the risk of cardiovascular and thromboembolic diseases due to heightened prothrombotic states, suggesting shared genetic determinants with thrombophilia. In addition, convergence of these polymorphisms to insulin resistance, a hallmark feature...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42538877
DOI: 10.1080/17520363.2026.2697763
PMCID: PMC13456514

Genes

FGB
MTHFR

Variants

rs6020
rs6020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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