Exploring imputation performance of phenotype-associated SNPs for forensic prediction models.

Abstract excerpt

Imputing single nucleotide polymorphisms (SNPs) to expand genotyped SNP panels is commonly applied to study genotype-phenotype correlations in medical and population genetics but is largely unexplored in forensics. Forensic DNA phenotyping, i.e., the SNP-based phenotype prediction, can greatly benefit from imputing missing prediction model SNPs. Unfortunately, most imputation studies investigate the performance...

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