Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Selective pressure-driven identification of conserved regions for Oropouche virus molecular detection.

Diagnostic microbiology and infectious disease - 1 Nov 2026

Avendano Andrea, Mavian Carla, Balzano-Nogueira Leandro, Ait Said Melissa, Salemi Marco, Paniz-Mondolfi Alberto

Abstract excerpt

Oropouche virus (OROV) is an emerging virus that causes a wide spectrum of febrile illnesses in humans. In this study, we examined two of the most commonly used primer sets for the clinical diagnosis of OROV to identify potential reduction in diagnostic sensitivity or even escape due to genetic variability in the target regions of circulating strains. We also evaluated selective pressures on the S segment to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bunyaviridae Infections
Share to Conserved Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Primers

Share to Molecular Diagnostic Techniques

Share to Phylogeny

Share to RNA, Viral

Share to Selection, Genetic

Share to Sensitivity and Specificity

Source

Identifiers

PMID: 42485961
DOI: 10.1016/j.diagmicrobio.2026.117559

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Selective pressure-driven identification of conserved regions for Oropouche virus molecular detection.PMID 42485961Read ↗

Development and validation of a multiplexed quantitative PCR assay for clinical detection and surveillance of Oropouche virusSemantic proximity Read ↗

Serological and viral prevalence of Oropouche virus (OROV): A systematic review and meta-analysis from 2000-2024 including human, animal, and vector surveillance studiesSemantic proximity Read ↗

Genomic and phenotypic characterization of the Oropouche virus strain implicated in the 2022-24 large-scale outbreak in Brazil.Semantic proximity Read ↗

Genomic and phenotypic characterization of an Oropouche virus strain implicated in the 2023-24 large-scale outbreak in BrazilSemantic proximity Read ↗

A Review of the Molecular Understanding of the Mpox Virus (MPXV): Genomics, Immune Evasion, and Therapeutic TargetsSemantic proximity Read ↗

Rapid Viral Expansion Beyond the Amazon Basin: Increased Epidemic Activity of Oropouche Virus Across the AmericasSemantic proximity Read ↗

Oropouche virus cases identified in Ecuador using an optimised qRT-PCR informed by metagenomic sequencingSemantic proximity Read ↗

Oropouche Virus: Clinical, Epidemiological, and Molecular Aspects of a Neglected Orthobunyavirus.Semantic proximity Read ↗

Oropouche virus: A neglected global arboviral threatSemantic proximity Read ↗

Molecular Epidemiology of Oropouche Virus, Ceará State, Brazil, 2024Semantic proximity Read ↗

Clinical Sequencing Uncovers Origins and Evolution of Lassa Virus.Semantic proximity Read ↗

Molecular epidemiology of Oropouche virus, Brazil.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.