Anti-GPIIIa antibody and CD4 count identify an autoimmune-enriched phenotype of HIV-associated thrombocytopenia: development and internal validation of a clinical nomogram.

Abstract excerpt

Background: Thrombocytopenia is a frequent complication of human immunodeficiency virus (HIV) infection, tire arising through diverse mechanisms including autoimmune platelet destruction, advanced immunodeficiency, and systemic comorbidities. Distinguishing thrombocytopenia driven primarily by autoimmune platelet destruction from that related to advanced immunodeficiency remains a clinical challenge, as current...

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