Article
There is no association between microRNA gene polymorphisms and risk of triple negative breast cancer in a Chinese Han population.
PloS one - 1 Jan 2013
Ma Fei, Zhang Ping, Lin Dongxin, Yu Dianke, Yuan Peng, Wang Jiayu, Fan Yin, Xu Binghe
Abstract excerpt
Triple-negative breast cancer (TNBC) is defined by the lack of the expression of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2). It is characterized by aggressive behavior, poor prognosis and lack of targeted therapies. MicroRNA (miRNA) as a novel modulator of gene expression has played an important regulatory role in the malignancy. Dysregulation and/or...
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