Article
Multifaceted roles of long non-coding RNAs in triple-negative breast cancer: biology and clinical applications.
Biochemical Society transactions - 18 Dec 2020
Rajagopal Taruna, Talluri Srikanth, Venkatabalasubramanian Sivaramakrishnan, Dunna Nageswara Rao
Abstract excerpt
Triple-negative breast cancer (TNBC) is a heterogeneous breast cancer subtype that lacks targeted therapy due to the absence of estrogen, progesterone, and HER2 receptors. Moreover, TNBC was shown to have a poor prognosis, since it involves aggressive phenotypes that confer significant hindrance to therapeutic treatments. Recent state-of-the-art sequencing technologies have shed light on several long non-coding...
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