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Article

Impact of Dietary Nut and DNA Methyltransferase 1 rs16999593 Polymorphism on Gastric Cancer Risk: Evidence from a Korean Hospital-Based Case-Control Study.

The Journal of nutrition - 1 Sept 2026

Gunathilake Madhawa, Kim Minseo, Lee Jeonghee, Choi Il Ju, Kim Young-Il, Kim Jeongseon

Abstract excerpt

BACKGROUND: Both genetic and epigenetic changes, particularly deoxyribonucleic acid (DNA) methylation, play crucial roles in gastric cancer development. Nuts, highlighted for their anti-inflammatory effects, may help maintain proper DNA methylation patterns. Thus, we hypothesized that high intake of nuts may interact with the DNA methylation-related genetic factor, DNA methyltransferase 1 (DNMT1) rs16999593...

Read the complete abstract on PubMed

Topics

Humans
Stomach Neoplasms
Female
Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

DNA (Cytosine-5-)-Methyltransferase 1

Middle Aged

Nuts

Republic of Korea

Male

Diet

DNA (Cytosine-5-)-Methyltransferases

Risk Factors

Genetic Predisposition to Disease

Polymorphism, Single Nucleotide

Aged

DNA Methylation

Adult

Source

Identifiers

PMID: 42468721
DOI: 10.1016/j.tjnut.2026.101734

Genes

DNMT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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