Article
Untangling the Copy Number Variation at the Basis of Belted Phenotypes in Cattle Using Long-Read Sequencing.
Animal genetics - 1 Aug 2026
Hogers Rensco A H, Bosse Mirte, Rattink Annemieke P, González-Prendes Rayner, Gòdia Marta, Laport Kimberley, Groenen Martien A M, Crooijmans Richard P M A, Bouwman Aniek C
Abstract excerpt
The belted phenotype in cattle, a distinctive white belt across the midsection observed in breeds such as the Dutch Belted and Belted Galloway, is caused by a copy number variant (CNV) upstream of TWIST2, a gene involved in melanocyte development. While the CNV is necessary for belt formation, the genetic basis of variation in belt width and completeness remains unclear. To refine understanding of these...
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