Article
Prognostic host phenotypes based on body composition and systemic inflammation predict survival in patients with resected pancreatic and periampullary cancer.
European journal of cancer (Oxford, England : 1990) - 9 Sept 2026
Hildebrand Nicole D, van Dijk David P J, Puik Jisce R, Henry Anne Claire, Andel Paul, Dekker Esther N, Michiels Nynke, Brandts Lloyd, Brecheisen Ralph, Wee Leonard, Festen Sebastiaan, Bosscha Koop, Schreinemakers Jennifer M J, Wit Fennie, van der Kolk Marion B, Mieog J Sven D, Liem Mike S L, Nieuwenhuijs Vincent B, de Hingh Ignace H J T, de Vos-Geelen Judith, Siveke Jens T, Klaase Joost M, de Meijer Vincent E, de Haas Robbert J, Groot Koerkamp Bas, Zonderhuis Babs M, Kazemier Geert, Besselink Marc G, Molenaar I Quintus, Daamen Lois A, den Dulk Marcel, Rensen Sander S, van Santvoort Hjalmar C, Olde Damink Steven W M
Abstract excerpt
INTRODUCTION: Most present-day survival-models of patients with cancer do not account for tumor-host interactions. We hypothesized that host phenotypes based on systemic inflammation and body composition are prognostic of overall survival (OS) in patients with pancreatic ductal adenocarcinoma (PDAC). METHODS: We performed a post-hoc analysis of the nationwide PORSCH-trial, including all patients undergoing...
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