Article
Investigating the role of FOF1 ATPase in Zymomonas mobilis through deletion of its FO and F1 subcomplexes.
Microbial cell factories - 13 Jul 2026
Behrendt Gerrich, Rutkis Reinis, Kalnenieks Uldis, Bettenbrock Katja
Abstract excerpt
Zymomonas mobilis has a typical FOF1 ATPase, yet does not exhibit oxidative phosphorylation. In order to investigate the function of the ATPase we sought to delete the FO and the F1 subcomplexes, respectively. Clean mutants could be obtained after selection under aerobic conditions. Growth analysis of the mutants showed that they strictly require oxygen for growth and that the oxygen supply is a factor...
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