Comparative analysis of genetic distribution of bovine spongiform encephalopathy (BSE)-related single nucleotide polymorphisms (SNPs) in the prion protein gene (PRNP) among three Korean cattle breeds.

Abstract excerpt

Prion protein, which is encoded by the prion protein gene (PRNP), is essential for the development of prion diseases, including bovine spongiform encephalopathy (BSE) in cattle. A previous study reported that two single nucleotide polymorphisms (SNPs), 4136 and 13861, in the bovine PRNP gene were associated with susceptibility to BSE in UK cattle. Although these two SNPs were briefly reported in Hanwoo and Korean...

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