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Article

Dissociable Neural Connectome Mapping of Reward and Punishment Responsiveness in Young Adults: Associations with Genetic Variability and Neurotransmitter Profiles.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 8 Oct 2025

Xu Ting, Zhu Chunhong, Zhou Xinqi, Chen Zhiyi, Gan Xianyang, Cui Xiaobing, Zhou Feng, Zhang Ran, Zhao Weihua, Zhang Xiaodong, Chen Hong, He Qinghua, Lei Xu, Qiu Jiang, Feng Tingyong

Abstract excerpt

While the hyper- and hypo-reward or punishment sensitivities (RS, PS) have received considerable attention as prominent transdiagnostic features of psychopathology, the lack of an overarching neurobiological characterization currently limits their early identification and neuromodulation. Here we combined microarray data from the Allen Human Brain Atlas with a multimodal fMRI approach to uncover the...

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PMID: 40903395
DOI: 10.1523/JNEUROSCI.0195-25.2025
PMCID: PMC12509494

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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