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Article

Alterations in resting-state functional activity and connectivity for major depressive disorder appetite and weight disturbance phenotypes.

Psychological medicine - 1 Jul 2023

Piccolo Mayron, Belleau Emily L, Holsen Laura M, Trivedi Madhukar H, Parsey Ramin V, McGrath Patrick J, Weissman Myrna M, Pizzagalli Diego A, Javaras Kristin N

Abstract excerpt

BACKGROUND: Major depressive disorder (MDD) is often accompanied by changes in appetite and weight. Prior task-based functional magnetic resonance imaging (fMRI) findings suggest these MDD phenotypes are associated with altered reward and interoceptive processing. METHODS: Using resting-state fMRI data, we compared the fractional amplitude of low-frequency fluctuations (fALFF) and seed-based connectivity (SBC)...

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Identifiers

PMID: 35670301
DOI: 10.1017/S0033291722001398
PMCID: PMC9949733

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