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Article

MTHFR, Pneumonia, and Thrombosis in Children: A Gene-Infection Interaction.

Pediatrics - 1 Aug 2026

Wang Fei, Li Runze, Cheng Qi, Li Jiujun, Chen Ning

Abstract excerpt

Severe pediatric pneumonia associated with thromboembolism is notable, yet its pathogenic mechanism remains elusive, suggesting a potential nonnegligible role of genetic susceptibility. Five previously healthy children were admitted with severe pneumonia, primarily caused by Mycoplasma pneumoniae and other pathogens. All patients exhibited markedly elevated inflammatory markers and D-dimer levels. Crucially,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42413940
DOI: 10.1542/peds.2025-075224

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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