Article
The life history of recessive deleterious alleles as seen through the eyes of a honey bee (Apis mellifera).
Molecular biology and evolution - 2 Jul 2026
Shultz Riley R, Nixon Jonathan M, Ryals Dylan K, Buschkoetter Amos C, Gilchrist Izaak R, Given J Krispn, Metz Bradley N, Magaña Armando Alcazar, Moon Kyung-Mee, Thanepohn Bobby, Mahood Julia, Tarpy David R, Foster Leonard J, Harpur Brock A
Abstract excerpt
Deleterious mutations arise continually in natural populations, yet their full life histories-from origin to elimination-are rarely observed directly. Our understanding of mutational fate in the wild comes from indirect inference rather than from tracking a single mutation through time and space. Haplodiploid systems provide a rare opportunity to observe negative selection in action: because males are haploid,...
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