Article
KCFtools: rapid alignment-free method for introgression screening and GWAS using k-mer profiles.
Bioinformatics (Oxford, England) - 2 Jul 2026
Selvanayagam Sivasubramani, Quiroz-Chavez Jesus, Ramirez-Gonzalez Ricardo H, Uauy Cristobal, Smit Sandra, Schranz M Eric
Abstract excerpt
MOTIVATION: In the era of multiple genome references, researchers often align sequencing reads against distinct assemblies or even multiple references simultaneously. This enables applications such as the detection of introgressed segments or highly variable genomic regions, which are especially prevalent in large-genome crop species such as lettuce or wheat. However, these applications come at the cost of...
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