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Article

Lactuca super-pangenome reduces bias towards reference genes in lettuce research.

BMC plant biology - 28 Oct 2024

van Workum Dirk-Jan M, Mehrem Sarah L, Snoek Basten L, Alderkamp Marrit C, Lapin Dmitry, Mulder Flip F M, Van den Ackerveken Guido, de Ridder Dick, Schranz M Eric, Smit Sandra

Abstract excerpt

BACKGROUND: Breeding of lettuce (Lactuca sativa L.), the most important leafy vegetable worldwide, for enhanced disease resistance and resilience relies on multiple wild relatives to provide the necessary genetic diversity. In this study, we constructed a super-pangenome based on four Lactuca species (representing the primary, secondary and tertiary gene pools) and comprising 474 accessions. We include 68 newly...

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PMID: 39468479
DOI: 10.1186/s12870-024-05712-2
PMCID: PMC11514843

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